Endocrine Abstracts

Introduction: Insulin autoimmune syndrome (IAS) is characterized by spontaneous hypoglycemia caused by insulin autoantibodies (IA) in the absence of exogenous insulin administration. The occurrence of IAS may be influenced by a genetic predisposition determined by HLA class II. IAS is frequently reported in Japanese and Koreans due to their genetic predisposition (HLA-DRB1*0406) rather than in the Caucasians. Some drugs containing sulfhydryl compounds are known to initiate the...